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Parvaneh Nakhostin Panahi

Maryam Alyari, Mojtaba Ghanbari Mehrabani, Maryam Allahvirdinesbat, Kazem D. Safa, Hossein Samadi Kafil, and Parvaneh Nokhostin Panahi
Ultrasound assisted Synthesis of Thiazolidine Thiones Containing1,2,3-triazoles Using Cu/TiO2
Abstract


Oxidised copper nanoparticles on TiO2 have been found to effectively catalyze the multicomponent synthesis of 1,4-disubstituted 1,2,3-triazoles in water under both conventional heating and ultrasonic irradiation conditions. The Cu/TiO2 nanocatalyst is easy to prepare, very versatile and recyclable. Following the optimized conditions, an array of 1,2,3-triazoles containing thiazolidine-2-thiones were synthesized from 5- iodomethylthiazolidine-2-thiones, sodium azide, and phenylacetylene. All the compounds were evaluated for antibacterial activitiy and some of them displayed varying levels of antibacterial activity against Staphylococcus aureus and Escherichia coli.

 

 

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