view:30188 Last Update: 2019-1-30
Ali Souldozi; Ali Ramazani; Nader Noshiranzadeh Dipotassium Hydrogen Phosphate Powder Catalyzed Stereoselective O-Vinylation of 1-(2-Hydroxy-1-naphthyl)-1-ethanone |
Protonation of the highly reactive 1:1 intermediates, produced in the reaction between triphenylphosphine and dialkyl acetylenedicarboxylates, by 1-(2-hydroxy-1- naphtyl)-1-ethanone leads to vinyltriphenylphosphonium salts, which undergo a Michael addition reaction with a conjugate base to produce corresponding stabilized phosphorus ylides. Dipotassium hydrogen phosphate powder was found to catalyze the conversion of stabilized phosphorus ylides to dialkyl ( E, Z)-2-(1-acetyl- 2-naphthyl)-2-butenedioates under thermal and microwave conditions in a solventless system |